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CLOSTNET - A Unique Opportunity to join a World - Class Research Team

22 PhD POSITIONS ACROSS 7 MEMBER STATES

1. Determination of the role of the global regulators agr and/or csrA in non-pathogenic and/or pathogenic clostridia (NOTTINGHAM, UK).
2. Identification of the regulatory factors that control the production of toxins in type A strains of C. perfringens associated with calf enterotoxaemia (EXETER, UK)
3. Analysis of the regulation of oxidative stress response in C. acetobutylicum (ROSTOCK, Germany) email for further details
4. To identify the role of sigma factors and two-component systems in C. botulinum at low temperature (HELSINKI, Finland) email for further details
5. To determine the role of quorum sensing in clostridial spore formation (NOTTINGHAM, UK) email for further details
6. Analysis of granulose storage in C. acetobutylicum (and other clostridia, e.g.,C. difficile) and its role in sporulation (ROSTOCK, Germany) email for further details
7. The identification of the mechanisms of germination, and subsequent growth and toxinogenesis in Group II type E C. botulinum (HELSINKI, Finland) email for further details
8. Effect of sporulation and germination on bacteriophage infection, lysogeny and bacteriophage-mediated lysis (CAMBRIDGE, UK) email for further details
9. Determination of the mechanism of toxin secretion in C. difficile (MARIBOR, Slovenia) email for further details
10. Elucidation of the C. perfringens secretome and its role in disease (BOXMEER, The Netherlands) email for futher details
11. To define the role of secreted toxins in veterinary disease caused by C. difficile (BOXMEER, The Netherlands) email for futher details
12. To identify the key chaperones involved in cellulosome component assembly and secretion. ( MARSEILLE
, France) email for further details
13. The secretome of C. perfringens and C. difficile: identification of novel secreted toxins (EXETER, UK) email for further details
14. Alcohologenesis in C. acetobutylicum (TOULOUSE, France) email for further details
15. Physiological characterization of “metabolic mutants” of C. acetobutylicum (TOULOUSE, France) email for further details
16. Regulation of the composition of the cellulolytic/ hemicellulolytic system of C. cellulolyticum ( MARSEILLE, France) email for further details
17. Effects of inactivation of key regulators of sporulation on C. acetobutylicum solventogenesis (MUNICH, Germany) email for further details
18. Molecular mechanisms influencing the variability of C. difficile (MARIBOR, Slovenia) email for further details
19. Definition of the mechanisms of antibiotic resistance in C.difficile (ROME, Italy) email for further details
20. Comparative genomic analysis of solventogenic clostridia and their megaplasmids (MUNICH, Germany) email for further details
21. Influence of antibiotic resistance on fitness and virulence of C.difficile (ROME, Italy) email for further details
22. Genetic characterisation of bacteriophage interaction with C. difficile with respect to host spectrum, lysogeny/lysis and induction (CAMBRIDGE, UK)
email for further details

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