Clostridium XII

International Conference on the Genetics, Physiology and Biotechnology of Solvent- and Acid-forming Clostridia

10 - 12 SEPTEMBER 2012



















Click on links to download a pdf of the oral presentations

Monday, 10th September 2012

 Session I: REGULATION                                  Adams Room, Nottingham Conference Centre

Chairperson:     Terry Papoutsakis

09.00 - 09.05     Nigel P Minton - The University of Nottingham, UK
Welcome and Introduction

09.05 - 09.40     Nigel P Minton - The University of Nottingham, UK
“A ‘Road Map’ for the Genetic Modification of Any Clostridium spp”

09.40 - 10.05     Peter Dürre - University of Ulm, Germany
“Master and Commander: Spo0A vs. SolB, a Small Regulatory RNA, in Controlling the Shift to Solventogenesis in Clostridium acetobutylicum”

10.05 - 10.30     Klaus Winzer - The University of Nottingham, UK
“Quorum Sensing regulates sporulation and solvent formation in Clostridium acetobutylicum

10.30 - 10.45     Delyana Vasileva - University of Rostock, Germany (Young Presenter)
Kindly sponsored by the BBSRC
“Iron-dependent Response of the Strict Anaerobe Clostridium acetobutylicum

10.45 - 11.15     Coffee break    

Chairperson:     Nigel P Minton

11.15 - 11.50     Weihong Jiang -Shanghai Institutes for Biological Sciences, China (Invited Speaker)
Kindly sponsored by the SfAM
“CcpA, a Pleiotropic Key Regulator in Butanol-producing Clostridium acetobutylicum”

11.50 - 12.15     Ralf-Jörg Fischer - University of Rostock, Germany
“Role of Granulose for Formation and SASPs for Germination of Endospores of Clostridium acetobutylicum”

12.15 - 12.40     Jeffrey Blanchard - The University of Massachusetts, USA
“Population Level Analysis of Mutations Underlying Improvements in Biofuel Production by Clostridium phytofermentans”

12.40 - 13.00     Steven Brown - Oak Ridge National Laboratory, USA
“RNA-Seq and DNA Microarray Analyses of Clostridium thermocellum Biomass Fermentation Transcriptomes”

 13.00 - 14.30     Lunch                                                              The Old Library, NCC

 Session II: BUTANOL ENGINEERING                                       Adams Room, NCC

Chairperson:     George Bennett

14.30 - 15.05     Isabelle Meynial-Salles - INSA, Toulouse, France (Invited Speaker)
Kindly sponsored by the SGM
“Metabolic Engineering of Clostridium acetobutylicum ATCC 824 for the High-Yield Production of Biofuels”
15.05 - 15.30     Edward Green - Green Biologics Ltd, UK
“Use of Municipal Solid Waste as a Feedstock for the Butanol Fermentation”

15.30 - 15.55     Shang-Tian Yang - The Ohio State University, USA
“Engineering Clostridium for High-Titer and High-Yield Biobutanol Production”

15.55 - 16.20     Ye Ni - Jiangnan University, China
“Continuous Butanol Fermentation from Low-Value Sugar-Based Feedstocks by Clostridium saccharobutylicum DSM 13864”

16.20 - 16.35    Holger Janssen - University of Illinois, USA
“Genome-wide Transcriptomic Analysis in Clostridium beijerinckii 8052 using Single-Nucleotide Resolution RNA-Seq Technology”

16. 35 - 18.00    Posters I & Coffee                                            Bowden Room, NCC

20.00 - 22.00     Dinner                                                              The Old Museum, NCC 

 Tuesday, 11th September 2012

Session III: CELLULOSE AND SUGAR UTILISATION                Adams Room, NCC

Chairperson:     Peter Dürre

09.00 - 09.35     Mike Himmel - NREL, USA (Invited Speaker)
Kindly sponsored by the BBSRC
"Engineering the Clostridium thermocellum cellulosome"

09.35 - 10.00     Lee Lynd - Dartmouth College, USA
“Clostridium thermocellum: Metabolic engineering and cellulose utilization”
10.00 - 10.25     Philippe Soucaille - INSA, France
“The Weizmann process revisited for cellulosic Butanol production”

10.25 - 10.45     David Ramey - Green Biologics Ltd, USA
“Cellulosic Butanol - A Sustainable Advanced Next Generation Biofuel”
10.45 - 11.00     Kousuke Yamamoto - Mie University, Japan (Young Presenter)
Kindly sponsored by the BBSRC
“Identification of the Clostridium cellulovorans cellulosomal subunits on soft biomass degradation”

11.00 - 11.25     Coffee break    

Chairperson:     Philippe Soucaille

11.25 - 12.00     Wilfrid Mitchell - Heriot-Watt University, UK (Invited Speaker)
Kindly sponsored by the SGM
“Glucose Sensing in the Solventogenic Clostridia”
12.00 - 12.25     Chen Yang - SIBS, China
“Pathway Reconstruction and Flux Quantification of Pentose Metabolism in Solventogenic Clostridia”

12.25 - 12.50     Katherine Germane - US Army Research Laboratory, USA
“Arabinose is Metabolized Via a Phosphoketolase Pathway in Clostridium acetobutylicum”

12.50 - 13.15     Ana Lopez-Contreras - Food & Biobased Research-Wageningen UR, The Netherlands
“Production of Acetone, Butanol and Ethanol from native North Sea seaweed species”

13.15 - 13.30     Kumaran Sivagnanam - McGill University, Canada (Young Presenter)
Kindly sponsored by the BBSRC
“Proteomic Analysis of Clostridium acetobutylicum from Butanol Fermentation”

13.30 - 14.30     Lunch                                                              The Old Library, NCC

 14.30 - 17.30     NETWORKING AFTERNOON                

 19.00 - 23.00     BBQ                                                                 The Old Chemistry Theatre, NCC

 Wednesday, 12th September 2012


Chairperson:     Weihong Jiang

09.00 - 09.35     Derek Lovley - University of Massachusetts, USA (Invited Speaker)
"Feeding Acetogenic Clostridia Electricity to Produce Organic Commodities from Carbon Dioxide"

09.35 - 10.00     Michael Koepke  - LanzaTech, New Zealand
"Production of Fuels and Chemicals from Industrial Waste Gases".”

10.00 - 10.25     Terry Papoutsakis - University of Delaware, USA
“Installing the Wood-Ljungdahl (WL) pathway in Clostridium acetobutylicum”
10.25 - 10.40     Simone Morra - University of Torino, Italy (Young Presenter)
Kindly sponsored by the BBSRC
“Clostridia from a Pilot Plant for Enhanced Hydrogen Gas Production: Isolation, Molecular Characterization and Hydrogenase Genes Cloning for Exploitation in Biotechnology”

10.40 - 11.10     Coffee break

Chairperson:     Wilfred Mitchell

11.10 - 11.35     David Levin - University of Manitoba, Canada
Central metabolism of the anaerobic lignocellulolytic thermophile Clostridium stercorarium subsp. stercorarium DSM8532

11.35 - 12.00     Thomas Millat - University of Rostock, Germany
“Mathematical Modelling of the pH-induced Metabolic Shift Unravels a Heterogeneous Phase Transition”

12.00 - 12.25     Servé Kengen - Wageningen University, The Netherlands
“Analysis of the Transcriptional Response to n-Butanol Challenges during Acidogenic Continuous Culturing of Clostridium acetobutylicum

12.25 - 12.50     Sebastian Curth - Beuth University of Applied Sciences Berlin, Germany
“Mathematical Modelling for Prediction of Strain Optimization Targets: Sensitivity Analysis and Evaluation of Dynamic Experiments”

12.50 - 13.05     Torbjørn Ølshøj Jensen - Aalborg University & Biogasol, Denmark (Young Presenter)
Kindly sponsored by the BBSRC
“Conversion of Crude Glycerol by Clostridium pasteurianum and by a Developed Mutant Strain”

13.05 - 14.30     Lunch                                                              The Old Library, NCC

 14.30 - 16.00     Posters II & Coffee                                           Bowden Room, NCC


Chairperson:     Klaus Winzer

16.00 - 16.35     Wolfgang Buckel - Philipps-Universität Marburg, Germany (Invited Speaker)
Kindly sponsored by the SfAM
"Radical enzymes in clostridial butyrate synthesis".

16.35 - 17.00     George Bennett - Rice University, USA
“Analysis of Redox Responses During TNT Transformation by Clostridium acetobutylicum ATCC824 and Mutants and Other Clostridia”

17.00 - 17.25     Tina Lütke-Eversloh - University of Rostock, Germany
“Development and Application of a High-throughput Screening System for Clostridial Biofuel Production”

17.25 - 17.50     Petra Patakova - Institute of Chemical Technology Prague, Czech Republic
“Flow Cytometry Analysis of Solventogenic Clostridia”

17.50 - 18.05     Swati Badgujar - Institute of Chemical Technology, Mumbai, India (Young Presenter)
Kindly sponsored by the BBSRC
“Carbon flux diversion in Clostridium acetobutylicum : Effect of Mutagenesis and Stress” 

18.05 - 18-10     Closing Remarks

 20.00 - 22.00     Conference Dinner                                           The Old Museum, NCC